Evaluation of geranylgeranyl diphosphate synthase inhibition as a novel strategy for the treatment of osteosarcoma and Ewing sarcoma-Reference-Cited by-同舟云学术

Evaluation of geranylgeranyl diphosphate synthase inhibition as a novel strategy for the treatment of osteosarcoma and Ewing sarcoma

Published:2022-11-25 Issue:1 Volume:84 Page:62-74
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Development Research

Author:

Haney Staci L.¹,Feng Dan¹,Chhonker Yashpal S.²,Varney Michelle L.¹,Williams Jacob T.¹,Smith Lynette M.³,Ford James B.⁴,Murry Daryl J.²,Holstein Sarah A.¹^ORCID

Affiliation:

1. Department of Internal Medicine University of Nebraska Medical Center Omaha Nebraska USA

2. Department of Pharmacy Practice and Science University of Nebraska Medical Center Omaha Nebraska USA

3. Department of Biostatistics University of Nebraska Medical Center Omaha Nebraska USA

4. Department of Pediatrics University of Nebraska Medical Center Omaha Nebraska USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Drug Discovery

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.22012

Reference34 articles.

1. Proteomics and phosphoproteomics provide insights into the mechanism of action of a novel pyrazolo[3,4-d]pyrimidine Src inhibitor in human osteosarcoma

2. Upregulation of the Mevalonate Pathway through EWSR1-FLI1/EGR2 Regulatory Axis Confers Ewing Cells Exquisite Sensitivity to Statins

3. IMPDH2 and HPRT expression and a prognostic significance in preoperative and postoperative patients with osteosarcoma

4. Protein profiling of osteosarcoma tissue and soft callus unveils activation of the unfolded protein response pathway

5. Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS

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