A validated LC–MS/MS method for simultaneous quantification of simvastatin and simvastatin acid in beagle plasma: Application to an absolute bioavailability study-Reference-Cited by-同舟云学术

A validated LC–MS/MS method for simultaneous quantification of simvastatin and simvastatin acid in beagle plasma: Application to an absolute bioavailability study

Published:2022-01-13 Issue: Volume: Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Zhang Yu¹²^ORCID,He Jian¹²,Tang Xiao¹²,Zhang Zunjian¹^ORCID,Tian Yuan¹^ORCID

Affiliation:

1. Key Laboratory of Drug Quality Control and Pharmacovigilance (China Pharmaceutical University) Ministry of Education Nanjing China

2. Key Laboratory of Drug Consistency Evaluation China Pharmaceutical University Nanjing China

Funder

National Science and Technology Major Project

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.5290

Reference21 articles.

1. Preparation and evaluation of mucoadhesive simvastatin microcapsules using orifice gelation technique;Bal T.;Asian Journal of Pharmaceutics,2012

2. Validated HPLC–MS/MS method for simultaneous determination of simvastatin and simvastatin hydroxy acid in human plasma

3. Incorporation of simvastatin into lipid membranes: Why deliver a statin in form of inclusion complex with hydrophilic cyclodextrin

4. Pleiotropic effects of statins: new therapeutic targets in drug design

5. In vitro and in vivo investigation of the gastrointestinal behavior of simvastatin

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