Common chromosomal fragile siteFRA16Dtumor suppressorWWOXgene expression and metabolic reprograming in cells
Author:
Affiliation:
1. Discipline of Genetics; School of Molecular and Biomedical Sciences and ARC Special Research Centre for the Molecular Genetics of Development, The University of Adelaide; Adelaide SA 5005 Australia
Publisher
Wiley
Subject
Cancer Research,Genetics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/gcc.22078/fullpdf
Reference44 articles.
1. Targeted deletion of Wwox reveals a tumor suppressor function;Aqeilan;Proc Natl Acad Sci U S A,2007
2. The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism;Aqeilan;J Biol Chem,2008
3. Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis;Aqeilan;Endocrinology,2009
4. WWOX, the FRA16D gene, behaves as a suppressor of tumor growth;Bednarek;Cancer Res,2001
5. Report of the committee on chromosome rearrangements in neoplasia and on fragile sites;Berger;Cytogenet Cell Genet,1985
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1. WWOX P47T partial loss-of-function mutation induces epilepsy, progressive neuroinflammation, and cerebellar degeneration in mice phenocopying human SCAR12;Progress in Neurobiology;2023-04
2. WWOX P47T loss-of-function mutation induces epilepsy, progressive neuroinflammation, and cerebellar degeneration in mice phenocopying human SCAR12;2022-10-07
3. The WWOX/HIF1A Axis Downregulation Alters Glucose Metabolism and Predispose to Metabolic Disorders;International Journal of Molecular Sciences;2022-03-19
4. Molecular Biology of the WWOX Gene That Spans Chromosomal Fragile Site FRA16D;Cells;2021-06-29
5. The WWOX Gene Influences Cellular Pathways in the Neuronal Differentiation of Human Neural Progenitor Cells;Frontiers in Cellular Neuroscience;2019-08-30
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