PLLA‐Based Block Copolymers via Raft Polymerization—Impact of the Synthetic Route and Activation Mechanism

Author:

Alsawaf Ahmad1,Kanehira Yuya1,Bapolisi Alain M.1,Bald Ilko1ORCID,Hartlieb Matthias12ORCID

Affiliation:

1. Institute of Chemistry University of Potsdam Karl‐Liebknecht‐Str. 24–25 14476 Potsdam Germany

2. Fraunhofer Institute for Applied Polymer Research (IAP) Geiselbergstraße 69 14476 Potsdam Germany

Abstract

AbstractDesigning supramolecular structures with well‐defined dimensions and diverse morphologies via the self‐assembly of block copolymers is renowned. Specifically, the design of 1D fiber nanostructures is extensively emphasized, due to their unique properties in many areas, such as microelectronics, photonics, and particularly in the biomedical field. Herein, amphiphilic diblock copolymers of P(l‐lactide)‐b‐P(N‐t‐butoxy‐carbonyl‐N´‐acryloyl‐1,2‐diaminoethane)‐co‐P(N‐isopropylacrylamide) PLLAnb‐P(BocAEAm)mco‐ P(NiPAAm)Ɩ are developed. Two synthetic strategies are investigated to equip PLLA with a chain transfer agent (CTA), either by Steglich esterification of PLLA‐OH or via the ring‐opening polymerization of l‐lactide using a CTA containing a hydroxyl functional group. The second strategy proves to be superior in terms of degree of functionalization. The corona‐forming blocks, with degrees of polymerization of 200 and above are achieved in good definition by photo‐iniferter RAFT polymerization (Đ ≤ 1.25), while a Đ of 1.75 is obtained by conventional RAFT polymerization. The self‐assembly of the developed system leads to the formation of nanofibers with a height of 11 nm and a length of ≈300 nm, which is determined by atomic force microscopy (AFM). These fibers are the basis for new antimicrobial nanomaterials after deprotection, as the subject of upcoming work.

Funder

European Research Council

Publisher

Wiley

Subject

Materials Chemistry,Organic Chemistry,Polymers and Plastics,Physical and Theoretical Chemistry,Condensed Matter Physics

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3