Robust design and optimization of retroaldol enzymes

Author:

Althoff Eric A.,Wang Ling,Jiang Lin,Giger Lars,Lassila Jonathan K.,Wang Zhizhi,Smith Matthew,Hari Sanjay,Kast Peter,Herschlag Daniel,Hilvert Donald,Baker David

Funder

National Institutes of Health

Defense Advances Research Projects Agency

the Howard Hughes Medical Institute

the Schweizerischer Nationalfonds

Ruth L. Kirschstein National Research Service Awards

the Stipendienfonds der Schweizerischen Chemischen Industrie

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference29 articles.

1. De novo computational design of retro-aldol enzymes;Jiang;Science,2008

2. Kemp elimination catalysts by computational enzyme design;Röthlisberger;Nature,2008

3. Enzyme-like proteins by computational design;Bolon;Proc Natl Acad Sci USA,2001

4. De novo design of catalytic proteins;Kaplan;Proc Natl Acad Sci USA,2004

5. Critical analysis of antibody catalysis;Hilvert;Annu Rev Biochem,2000

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