Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery-Reference-Cited by-同舟云学术

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Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery

Published:2016-03-21 Issue:4 Volume:5 Page:357-368
ISSN:2191-1363
Container-title:ChemistryOpen
language:en
Short-container-title:ChemistryOpen

Author:

Mao Fei¹,Kong Qingya¹,Ni Wei¹,Xu Xiang¹,Ling Dazheng¹,Lu Zhengyu¹,Li Jian¹

Affiliation:

1. Shanghai Key Laboratory of New Drug Design; School of Pharmacy; East China University of Science and Technology; 130 Mei Long Road Shanghai 200237 P. R. China

Funder

National Natural Science Foundation of China

Program for New Century Excellent Talents in University

Shanghai Municipal Education Commission and Shanghai Education Development Foundation

Fundamental Research Funds for the Central Universities

Publisher

Wiley

Subject

General Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/open.201600015/fullpdf

Reference27 articles.

1. Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

2. An analysis of the attrition of drug candidates from four major pharmaceutical companies

3. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

4. Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

5. Time-Related Differences in the Physical Property Profiles of Oral Drugs

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