Challenges and Opportunities for Improved Drug–Drug Interaction Predictions for Renal OCT2 and MATE1/2‐K Transporters-Reference-Cited by-同舟云学术

Challenges and Opportunities for Improved Drug–Drug Interaction Predictions for Renal OCT2 and MATE1/2‐K Transporters

Published:2022-06-25 Issue:3 Volume:112 Page:562-572
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharma and Therapeutics

Author:

Krishnan Srinivasan¹,Ramsden Diane¹^ORCID,Ferguson Douglas¹,Stahl Simone H.²^ORCID,Wang Joanne³,McGinnity Dermot F.⁴,Hariparsad Niresh¹^ORCID

Affiliation:

1. Drug Metabolism and Pharmacokinetics, Oncology Research & Development AstraZeneca Boston Massachusetts USA

2. Cardiovascular, Renal, and Metabolism Safety, Clinical Pharmacology and Safety Sciences, Research & Development AstraZeneca Cambridge UK

3. Department of Pharmaceutics University of Washington Seattle Washington USA

4. Drug Metabolism and Pharmacokinetics, Oncology Research & Development AstraZeneca Cambridge UK

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2666

Reference46 articles.

1. Evaluation and Quantitative Prediction of Renal Transporter-Mediated Drug-Drug Interactions

2. Cloning and Characterization of Two Human Polyspecific Organic Cation Transporters

3. A human transporter protein that mediates the final excretion step for toxic organic cations

4. US Food and Drug Administration.In vitrodrug interaction studies–cytochrome P450 enzyme‐ and transporter‐ mediated drug interaction guidance for industry(January 2020).

5. European Medicines Agency.Guideline on the investigation of drug interactions(June 2012).

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