Assessment of Biliary Clearance in Early Drug Discovery using Sandwich-cultured Hepatocyte Model
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference38 articles.
1. Use of cryopreserved human hepatocytes in sandwich culture to measure hepatobiliary transport;Bi;Drug Metab Dispos,2006
2. In silico prediction of biliary excretion of drugs in rats based on physicochemical properties;Luo;Drug Metab Dispos,2010
3. Prediction of biliary excretion in rats and humans using molecular weight and quantitative structure–pharmacokinetic relationships;Yang;AAPS J,2009
4. Sandwich-cultured hepatocytes: An in vitro model to evaluate hepatobiliary transporter-based drug interactions and hepatotoxicity;Swift;Drug Metab Rev,2010
5. P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: Relevance to the hepatobiliary disposition of a model opioid peptide;Hoffmaster;Pharm Res,2004
Cited by 25 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Culture methods focusing on bile canalicular formation using primary human hepatocytes in a short time;In Vitro Cellular & Developmental Biology - Animal;2023-09
2. Discovery of orally effective and safe GPR40 agonists by incorporating a chiral, rigid and polar sulfoxide into β-position to the carboxylic acid;European Journal of Medicinal Chemistry;2023-05
3. FEK self‐assembled peptide hydrogels facilitate primary hepatocytes culture and pharmacokinetics screening;Journal of Biomedical Materials Research Part B: Applied Biomaterials;2022-03-18
4. Mechanistic study on the species differences in excretion pathway of HR011303 in human and rats;Drug Metabolism and Disposition;2021-12-03
5. Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity;Drug Metabolism and Disposition;2021-02-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3