Treatment‐induced neuropathy of diabetes: an update

Author:

Quiroz‐Aldave Juan Eduardo1,Concepción‐Zavaleta Marcio José2,del Carmen Durand‐Vásquez María3,Gamarra‐Osorio Elman Rolando4,Alcalá‐Mendoza Rosa María5,Puelles‐León Susan Luciana6,Ildefonso‐Najarro Sofía7,Concepción‐Urteaga Luis Alberto8,Gonzáles‐Mendoza Jorge Estanislao9,Paz‐Ibarra José10

Affiliation:

1. Division of Medicine, Hospital de Apoyo Chepén, Chepén Perú

2. Carrera de Medicina Humana, Universidad Científica del Sur, Lima Perú

3. Division of Family Medicine, Hospital de Apoyo Chepén, Chepén Perú

4. Division of Endocrinology, Hospital Víctor Lazarte Echegaray, Trujillo Perú

5. Division of Physical Medicine and Rehabilitation, Hospital Víctor Lazarte Echegaray, Trujillo Perú

6. Division of Internal Medicine, Hospital de Apoyo Chepén, Chepén Perú

7. Division of Endocrinology. Hospital Nacional Guillermo Almenara Irigoyén, Lima Perú

8. School of Medicine, National University of Trujillo, Trujillo Perú

9. Alexander von Humboldt Institute of Tropical Medicine Peruvian University Cayetano Heredia, Lima Perú

10. School of Medicine National University of San Marcos, Lima Perú

Abstract

Abstract Background and aims: Treatment‐induced neuropathy of diabetes is an acute small‐fibre neuropathy associated with rapid glycaemia improvement.Methods: This study is a narrative review carried out based on a bibliographic review, using articles indexed in PubMed/Medline and Scielo.Results: This entity is more frequent in adult patients with poor previous glycaemic control. Its precise pathophysiology is unknown, but it is likely related to unrestored microcirculation changes that occurred during the hyperglycaemic period. It presents with intense, sudden neuropathic pain and autonomic dysfunction after a rapid glycaemic correction and a poorer analgesic response than in diabetic neuropathy.Conclusions: Since rapid glycaemia correction is the cause of this problem, clinical practice guidelines that can help physicians to prevent, diagnose and manage this entity should be developed. Copyright © 2023 John Wiley & Sons.

Publisher

Wiley

Subject

Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference57 articles.

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