Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses

Author:

Nakayama Taisuke1,Mizohata Eiichi1,Yamashita Takefumi2,Nagatoishi Satoru3,Nakakido Makoto3,Iwanari Hiroko4,Mochizuki Yasuhiro4,Kado Yuji1,Yokota Yuki1,Satoh Reiko1,Tsumoto Kouhei3,Fujitani Hideaki2,Kodama Tatsuhiko2,Hamakubo Takao4,Inoue Tsuyoshi1

Affiliation:

1. Structural Physical Chemistry; Division of Applied Chemistry; Graduate School of Engineering; Osaka University; Osaka Japan

2. Laboratory for Systems Biology and Medicine; Research Center for Advanced Science and Technology, The University of Tokyo; Tokyo Japan

3. Medical Proteomics Laboratory; The Institute of Medical Science, The University of Tokyo; Tokyo Japan

4. Department of Quantitative Biology and Medicine; Research Center for Advanced Science and Technology, The University of Tokyo; Tokyo Japan

Funder

Japan Science and Technology Agency

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science, and Technology

FIRST Program, Japan Society for the Promotion of Science

SACLA Project, Japan Synchrotron Radiation Research Institute

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference40 articles.

1. Improving the efficacy of antibody-based cancer therapies;Carter;Nat Rev Cancer,2001

2. Identification and validation of cell surface antigens for antibody targeting in oncology;Carter;Endocr Relat Cancer,2004

3. Pretargeting strategies for radio-immunoguided tumour localisation and therapy;Stoldt;Eur J Cancer,1997

4. Molecular advances in pretargeting radioimunotherapy with bispecific antibodies;Chang;Mol Cancer Ther,2002

5. Computational design of antibody-affinity improvement beyond in vivo maturation;Lippow;Nat Biotechnol,2007

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3