Amitriptyline protects against TNF-α-induced atrophy and reduction in synaptic markers via a Trk-dependent mechanism-Reference-Cited by-同舟云学术

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Amitriptyline protects against TNF-α-induced atrophy and reduction in synaptic markers via a Trk-dependent mechanism

Published:2016-03-08 Issue:2 Volume:4 Page:e00195
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

O'Neill Eimear¹²,Kwok Billy²,Day Jennifer S.²,Connor Thomas J.²,Harkin Andrew¹

Affiliation:

1. Neuropsychopharmacology Research Group; School of Pharmacy & Pharmaceutical Sciences and Trinity College Institute of Neuroscience; Dublin Ireland

2. Neuroimmunology Research Group; Department of Physiology; School of Medicine and Trinity College Institute of Neuroscience; Dublin Ireland

Funder

European Regional Development Fund

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Reference68 articles.

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2. Inflammation in central nervous system injury;Allan;Philos Trans R Soc Lond B Biol Sci,2003

3. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism;Block;Prog Neurobiol,2005

4. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding;Bradford;Anal Biochem,1976

5. The metabolic fate of amitriptyline, nortriptyline and amitriptylinoxide in man;Breyer-Pfaff;Drug Metab Rev,2004

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1. BDNF/TrkB activators in Parkinson's disease: A new therapeutic strategy;Journal of Cellular and Molecular Medicine;2024-05

2. Resolving a paradox: antidepressants, neuroinflammation, and neurodegeneration;Exploration of Neuroprotective Therapy;2024-02-23

3. Toward in vivo proof of binding of 18F-labeled inhibitor [18F]TRACK to peripheral tropomyosin receptor kinases;EJNMMI Research;2022-07-30

4. Amitriptyline Decreases GABAergic Transmission in Basal Forebrain Neurons Using an Optogenetic Model of Aging;Frontiers in Aging Neuroscience;2021-05-28

5. Kynurenic Acid Protects Against Reactive Glial-associated Reductions in the Complexity of Primary Cortical Neurons;Journal of Neuroimmune Pharmacology;2021-01-03

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