Seroma formation after mastectomy: A systematic review and network meta‐analysis of different flap fixation techniques

Author:

Spiekerman van Weezelenburg Merel A.1ORCID,Daemen Jean H. T.1,van Kuijk Sander M. J.2,van Haaren Elisabeth R. M.1ORCID,Janssen Alfred1,Vissers Yvonne L. J.1,Beets Geerard L.34,van Bastelaar James1ORCID

Affiliation:

1. Department of Surgery Zuyderland Medical Centre Sittard‐Geleen The Netherlands

2. Department of Clinical Epidemiology and Medical Technology Assessment Maastricht University Medical Centre Maastricht The Netherlands

3. Department of Surgery Netherlands Cancer Institute Amsterdam The Netherlands

4. GROW School for Oncology and Developmental Biology University of Maastricht Maastricht The Netherlands

Abstract

AbstractFlap fixation is the most promising solution to prevent seroma formation after mastectomy. In this systematic review with network meta‐analysis (NMA), three different techniques were compared. The NMA included 25 articles, comprising 3423 patients, and revealed that sutures are superior to tissue glue in preventing clinically significant seroma. In addition, running sutures seemed to be superior to interrupted sutures. An RCT comparing these suture techniques seems necessary, given the quality and nature of existing literature.

Publisher

Wiley

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