Lyophilization stabilizes clinical‐stage core‐crosslinked polymeric micelles to overcome cold chain supply challenges

Author:

Ojha Tarun123,Hu Qizhi4,Colombo Claudio4,Wit Jan5,Geijn Michiel4,Steenbergen Mies J.2,Bagheri Mahsa2,Königs‐Werner Hiltrud6,Buhl Eva Miriam6,Bansal Ruchi13,Shi Yang1,Hennink Wim E.2,Storm Gert27,Rijcken Cristianne J. F.4,Lammers Twan127ORCID

Affiliation:

1. Department of Nanomedicine and Theranostics Institute for Experimental Molecular Imaging Faculty of Medicine RWTH Aachen University Aachen Germany

2. Department of Pharmaceutics Utrecht University Utrecht The Netherlands

3. Department of Medical Cell BioPhysics Faculty of Science and Technology University of Twente Translational Liver Research Enschede The Netherlands

4. Cristal Therapeutics Maastricht The Netherlands

5. Saudade Pharma Consultancy Eijsden The Netherlands

6. Electron Microscope Facility University Hospital RWTH RWTH Aachen University Aachen Germany

7. Department of Biomaterials Science and Technology Faculty of Science and Technology University of Twente Enschede The Netherlands

Funder

Deutsche Forschungsgemeinschaft

Bundesministerium für Bildung und Forschung

H2020 Marie Skłodowska-Curie Actions

Phospholipid Research Center

H2020 European Research Council

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

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