Biomedical application of microalgal‐biomaterials hybrid system

Author:

Li Yize1ORCID,Fan Yali1,Ye Shuo1,Xu Lingyun1,Wang Gezhen1,Lu Yuli1,Huang Suxiang1,Zhang Yingying1

Affiliation:

1. School of Medical Imaging Xuzhou Medical University Xuzhou China

Abstract

AbstractMicroalgae are a group of microorganisms containing chlorophyll A, which are highly photosynthetic and rich in nutrients. And they can produce multiple bioactive substances (peptides, proteins, polysaccharides, and fatty acids) for biomedical applications. Despite the unique advantages of microalgae‐based biotherapy, the insufficient treatment efficiency limits its further application. With the development of nanotechnology, the combination of microalgae and biomaterials can improve therapeutic efficacies, which has attracted increasing attention. In this microalgal‐biomaterials hybrid system, biomaterials with excellent optical and magnetic properties play an important role in biological therapy. Microalgae, as a natural vehicle, can increase oxygen content and alleviate hypoxia in diseased areas, further enhancing therapeutic effects. In this review, the synergistic therapeutic effects of microalgal‐biomaterials hybrid system in different diseases (cancer, myocardial infarction, ischemia stroke, chronic infection, and intestinal diseases) are comprehensively summarized.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Xuzhou Medical University

Publisher

Wiley

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