Heparosan Chain Characterization: Sequential Depolymerization of E. Coli K5 Heparosan by a Bacterial Eliminase Heparin Lyase III and a Bacterial Hydrolase Heparanase Bp to Prepare Defined Oligomers-Reference-Cited by-同舟云学术

Heparosan Chain Characterization: Sequential Depolymerization of E. Coli K5 Heparosan by a Bacterial Eliminase Heparin Lyase III and a Bacterial Hydrolase Heparanase Bp to Prepare Defined Oligomers

Published:2020-11-10 Issue:3 Volume:16 Page:2000336
ISSN:1860-6768
Container-title:Biotechnology Journal
language:en
Short-container-title:Biotechnol. J.

Author:

Datta Payel¹,Yan LuFeng¹²,Awofiranye Adeola¹,Dordick Jonathan S.¹³^ORCID,Linhardt Robert J.¹²³^ORCID

Affiliation:

1. Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute Troy NY 12180 USA

2. Department of Chemistry and Chemical Biology Rensselaer Polytechnic Institute Troy NY 12180 USA

3. Department of Chemical and Biological Engineering Rensselaer Polytechnic Institute Troy NY 12180 USA

Funder

National Science Foundation

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.202000336

Reference25 articles.

1. Bioengineered heparins and heparan sulfates

2. E. coli K5 fermentation and the preparation of heparosan, a bioengineered heparin precursor

3. Enzymatic Degradation of GlycosaminogIycans

4. Heparinase production by Flavobacterium heparinum

5. A Comparative Analysis of the Primary Sequences and Characteristics of Heparinases I, II, and III fromFlavobacterium heparinum

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