Increased recombinant adeno‐associated virus production by HEK293 cells using small molecule chemical additives
Author:
Affiliation:
1. Department of Chemical and Biological Engineering University of Sheffield Sheffield UK
2. Cell Line Development REGENXBIO Inc. Rockville Maryland USA
Publisher
Wiley
Subject
Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.202200450
Reference67 articles.
1. The once and future gene therapy
2. The clinical landscape for AAV gene therapies
3. Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy
4. Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus
5. Adeno-Associated Virus Genome Interactions Important for Vector Production and Transduction
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1. Multi‐omics kinetic analysis of recombinant adeno‐associated virus production by plasmid transfection of HEK293 cells;Biotechnology Progress;2024-01-30
2. Current avenues of gene therapy in Pompe disease;Current Opinion in Neurology;2023-07-19
3. Critical challenges and advances in recombinant adeno‐associated virus (rAAV) biomanufacturing;Biotechnology and Bioengineering;2023-05
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