Optimization of a transient antibody expression platform towards high titer and efficiency-Reference-Cited by-同舟云学术

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Optimization of a transient antibody expression platform towards high titer and efficiency

Published:2021-01-25 Issue:4 Volume:16 Page:2000251
ISSN:1860-6768
Container-title:Biotechnology Journal
language:en
Short-container-title:Biotechnol. J.

Author:

Greene Elizabeth¹,Cazacu Daniela¹,Tamot Ninkka²,Castellano Steven³,Datar Akshita¹,Kronkaitis Anthony¹,Gebhard Douglas¹,Reed Jon¹,Mawson Paul¹,Florin Lore⁴,Rossi Nicholas⁵,Lauer Anthony⁵,Juckem Laura⁵,Nixon Andrew¹,Wenger Till¹,Sen Saurabh¹^ORCID

Affiliation:

1. Boehringer Ingelheim Pharmaceuticals Inc. Ridgefield Connecticut USA

2. Janssen Biotherapeutics Spring House Pennsylvania USA

3. Duke University School of Medicine Durham North Carolina USA

4. Bristol Myers Squibb Redwood City California USA

5. MirusBio LLC Madison Wisconsin USA

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.202000251

Reference28 articles.

1. Reflections on more than 10 years of TGE approaches

2. Recent advances in mammalian protein production

3. High-level protein expression in scalable CHO transient transfection

4. Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics

5. High Throughput Transfection of HEK293 Cells for Transient Protein Production

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A high‐titer scalable Chinese hamster ovary transient expression platform for production of biotherapeutics;Biotechnology and Bioengineering;2024-08-05

2. PEI-Mediated Transient Gene Expression in CHO Cells;Methods in Molecular Biology;2024

3. Matrixed CDR grafting: A neoclassical framework for antibody humanization and developability;Journal of Biological Chemistry;2024-01

4. Bioactivity of recombinant humanized monoclonal antibody against HER2 in-vivo and in-vitro and its mechanism of action in ovarian cancer;Translational Cancer Research;2023-06

5. Comparison of vector elements and process conditions in transient and stable suspension HEK293 platforms using SARS-CoV-2 receptor binding domain as a model protein;BMC Biotechnology;2023-03-07

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