Regeneration of Capto Core 700 resin through high throughput and laboratory scale studies and impact on production of a SARS‐CoV‐2 vaccine candidate-Reference-Cited by-同舟云学术

Regeneration of Capto Core 700 resin through high throughput and laboratory scale studies and impact on production of a SARS‐CoV‐2 vaccine candidate

Published:2022-07-28 Issue:10 Volume:17 Page:2200191
ISSN:1860-6768
Container-title:Biotechnology Journal
language:en
Short-container-title:Biotechnology Journal

Author:

Konstantinidis Spyridon¹^ORCID,Reinhart Seth R.¹,Castagna Christine¹,Poplyk Murphy R.¹,Rustandi Richard R.²,Flor Kristen L.³,Acevedo‐Skrip Jillian²,Thompson Rachel²,Wang Christopher J.²,Wang Sheng‐Ching¹,Winters Michael A.¹

Affiliation:

1. Vaccine Process Research & Development Merck & Co., Inc. Rahway New Jersey USA

2. Vaccine Analytical Research & Development Merck & Co., Inc. Rahway New Jersey USA

3. Investigative Pathology MRL Merck & Co., Inc. Rahway New Jersey USA

Publisher

Wiley

Subject

Molecular Medicine,Applied Microbiology and Biotechnology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/biot.202200191

Reference26 articles.

1. PROCESS ECONOMIC DRIVERS IN INDUSTRIAL MONOCLONAL ANTIBODY MANUFACTURE

2. Optimising the design and operation of semi-continuous affinity chromatography for clinical and commercial manufacture

3. Cleaning-in-Place and Sanitization

4. Role of Cleaning-in-Place in the Purification of mAb Supernatants Using Continuous Cation Exchange Chromatography

5. A safe, effective, and facility compatible cleaning in place procedure for affinity resin in large-scale monoclonal antibody purification

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