Affiliation:
1. College of Materials and Fujian Provincial Key Laboratory of Materials Genome Xiamen University Xiamen 361005 China
2. Helmholtz-Zentrum Hereon Institute of Materials Physics Max-Planck-Straße 1 21502 Geesthacht Germany
3. Helmholtz-Zentrum Hereon Institute of Metallic Biomaterials Max-Planck-Straße 1 21502 Geesthacht Germany
4. Jiangsu Gian Technology Co., Ltd. No. 59 Zonglv Road Changzhou 213000 China
5. State Key Laboratory of Advanced Welding and Joining Harbin Institute of Technology Shenzhen 518055 China
6. Institute of Materials Genome and Big Data, Harbin Institute of Technology Shenzhen 518055 China
Abstract
Titanium and its alloys are widely used as implant biomaterials due to their well mechanical properties and biological compatibilities. Nb and Mn are well‐known alloying elements with biological potential. Herein, the Ti–Mn–Nb phase equilibria at 900 °C (Ti‐rich region) is determined and published. According to the β single‐phase field in this phase diagram (at 900 °C), Ti–xMn–yNb (x = 4, 10, 16; y = 2, 8, 14, at%) alloys are selected and fabricated which are suited for solution heat treatment. The Ti–Mn–Nb alloys are investigated by optical microscopy (OM), X‐ray diffraction (XRD), and mechanical testing. A unique diffraction pattern (interpreted as occurrence of a transition phase) is observed by transmission electron microscopy (TEM) in Ti–10Mn–2Nb. In the in vitro evaluation, the human osteoblasts (MG63) adhere well and proliferate on the surface of Ti–xMn–yNb (x = 4, 10; y = 2, 8, 14, at%). According to cell culture experiments, the alloys are nontoxic to human osteosarcoma cells in comparison with pure titanium. Based on a performed screening study, different titanium alloys Ti–4Mn–yNb (y = 2, 8, 14) appear as the biomaterial with the highest potential around 700 MPa ultimate tensile strength and 9–10% elongation.
Funder
Joint Fund to Promote Cross-Straits Scientific and Technological Cooperation
Subject
Materials Chemistry,Electrical and Electronic Engineering,Surfaces, Coatings and Films,Surfaces and Interfaces,Condensed Matter Physics,Electronic, Optical and Magnetic Materials
Cited by
2 articles.
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