The clinical utility of PD-L1 testing in selecting non-small cell lung cancer patients for PD1/PD-L1-directed therapy

Author:

Villaruz LC1,Socinski MA1

Affiliation:

1. University of Pittsburgh Cancer Institute; Pittsburgh Pennsylvania USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference6 articles.

1. Nivolumab vs. Docetaxel in advanced squamous-cell non-small-cell lung cancer;Brahmer;N. Engl. J. Med.,2015

2. Nivolumab vs. Docetaxel in advanced nonsquamous non-small-cell lung cancer;Borghaei;N. Engl. J. Med.,2015

3. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial;Herbst;Lancet,2015

4. Late breaking abstract: Atezolizumab monotherapy vs docetaxel in 2L/3L non-small lung cancer: primary analyses for efficacy, safety, and predictive biomarkers from a randomized phase II study. (POPLAR);Vansteenkiste;Lancet,2016

5. Safety and clinical activity of MEDI4736, an anti-programmed cell death-ligand 1 (PD-L1) antibody, in patients with non-small cell lung cancer (NSCLC);Rizvi;J. Clin. Oncol.,2015

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