Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors

Author:

Liu Hui1ORCID,Dehestani Mohammad1,Blauwendraat Cornelis23ORCID,Makarious Mary B.2345,Leonard Hampton45,Kim Jonggeol J.26,Schulte Claudia1,Noyce Alastair6ORCID,Jacobs Benjamin M.6,Foote Isabelle6ORCID,Sharma Manu17ORCID,Koks Sulev,Mellick George D,Pirker Walter,Zimprich Alexander,Lang Anthony E,Rogaeva Ekaterina,Taba Pille,Brice Alexis,Chartier‐Harlin Marie‐Christine,Corvol Jean‐Christophe,Domenighetti Cloé,Elbaz Alexis,Lesage Suzanne,Mutez Eugenie,Sugier Pierre‐Emmanuel,Sreelatha Ashwin Ashok Kumar,Grover Sandeep,Brockmann Kathrin,Deutschländer Angela B,Gasser Thomas,Krüger Jens,Lichtner Peter,Radivojkov‐Blagojevic Milena,Schulte Claudia,Sharma Manu,Dardiotis Efthimos,Hadjigeorgiou Georges M,Simitsi Athina Maria,Stefanis Leonidas,Annesi Grazia,Brighina Laura,Ferrarese Carlo,Petrucci Simona,Pezzoli Gianni,Quattrone Andrea,Straniero Letizia,Gagliardi Monica,Valente Enza Maria,Zecchinelli Anna,Hattori Nobutaka,Nakayama Akiyoshi,Matsuo Hirotaka,Nishioka Kenya,Bobbili Dheeraj,Kruger Rejko,Landoulsi Zied,May Patrick,Pavelka Lukas,Bloem Bastiaan R,van de Warrenburg Bart PC,Aasly Jan,Pihlstrøm Lasse,Toft Mathias,Ferreira Joaquim J,Guedes Leonor Correia,Bardien Soraya,Carr Jonathan,Chung Sun Ju,Kim Yun Joong,Diez‐Fairen Monica,Ezquerra Mario,Pastor Pau,Tolosa Eduardo,Belin Andrea C,Pedersen Nancy L,Puschmann Andreas,Ran Caroline,Rödström Emil Y,Wirdefeldt Karin,Clarke Carl E,Morrison Karen E,Tan Manuela,Edsall Connor,Farrer Matt J,Krainc Dimitri,Singleton Andrew B,Burbulla Lena F,Hernandez Dena G,Nalls Mike34,Singleton Andrew23,Gasser Thomas1,Bandres‐Ciga Sara23ORCID,

Affiliation:

1. Department for Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research University of Tübingen and German Center of Neurodegenerative Diseases Tübingen Germany

2. Laboratory of Neurogenetics, Molecular Genetics Section, National Institute on Aging National Institutes of Health Bethesda MD USA

3. Center for Alzheimer's and Related Dementias National Institutes of Health Bethesda MD USA

4. Data Tecnica International Glen Echo MD USA

5. Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology London UK

6. Preventive Neurology Unit, Wolfson Institute of Population Health Queen Mary University of London London UK

7. Center for Genetic Epidemiology, Institute for Clinical Epidemiology and Functional Biometry University of Tübingen Tübingen Germany

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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