Dynamic transcription factor activity profiles reveal key regulatory interactions during megakaryocytic and erythroid differentiation

Author:

Duncan Mark T.1,Shin Seungjin1,Wu Jia J.12,Mays Zachary13,Weng Stanley1,Bagheri Neda1425,Miller William M.1425,Shea Lonnie D.14625

Affiliation:

1. Department of Chemical and Biological Engineering; Northwestern University; 2145 Sheridan Road Evanston Illinois 60208

2. Interdepartmental Biological Sciences Graduate Program (IBIS); Northwestern University; 2145 Sheridan Road Evanston Illinois 60208

3. Master of Biotechnology Program; Northwestern University; Evanston Illinois 60208

4. Robert H. Lurie Comprehensive Cancer Center of Northwestern University; 303 E. Superior Street Chicago Illinois 60611

5. Chemistry of Life Processes Institute (CLP); Northwestern University; Evanston Illinois 60208

6. Institute for Bionanotechnology in Medicine (IBNAM); Northwestern University; Chicago Illinois 60611

Funder

U.S. National Science Foundation (NSF)

National Institutes of Health (NIH)

NIH Predoctoral Biotechnology Training

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference59 articles.

1. Increased expression of the ETS-related transcription factor FLI-1/ERGB correlates with and can induce the megakaryocytic phenotype;Athanasiou;Cell Growth Differ,1996

2. FLI-1 is a suppressor of erythroid differentiation in human hematopoietic cells;Athanasiou;Leukemia,2000

3. Cellular arrays for large-scale analysis of transcription factor activity;Bellis;Biotechnol Bioeng,2011

4. Controlling the false discovery rate: A practical and powerful approach to multiple testing;Benjamini;J R Stat Soc Ser B Methodol,1995

5. Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner;Briegel;Genes Dev,1993

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