Efavirenz does not meaningfully affect the single dose pharmacokinetics of 1200 mg raltegravir
Author:
Affiliation:
1. Merck Research Laboratories; Merck & Co., Inc; Kenilworth NJ USA
2. Celerion; Lincoln NE USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/bdd.2045/fullpdf
Reference19 articles.
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2. Raltegravir once daily or twice daily in previously untreated patients with HIV-1: a randomised, active-controlled, phase 3 non-inferiority trial;Eron;Lancet Infect Dis,2011
3. Efavirenz: a review;Vrouenraets;Expert Opin Pharmacother,2007
4. Metabolism and disposition in humans of raltegravir (raltegravir), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme;Kassahun;Drug Metab Dispos,2007
5. Effect of rifampin, a potent inducer of drug-metabolizing enzymes, on the pharmacokinetics of raltegravir;Wenning;Antimicrob Agents Chemother,2009
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