Thioesterase Superfamily Member 2 Promotes Hepatic VLDL Secretion by Channeling Fatty Acids Into Triglyceride Biosynthesis

Author:

Alves‐Bezerra Michele1,Li Yingxia1,Acuña Mariana1,Ivanova Anna A.2,Corey Kathleen E.34,Ortlund Eric A.5,Cohen David E.1

Affiliation:

1. Joan & Sanford I. Weill Department of Medicine Weill Cornell Medical College New York NY

2. Emory Integrated Lipidomics Core, Emory University Atlanta GA

3. Gastrointestinal Unit Massachusetts General Hospital Boston MA

4. Harvard Medical School Boston MA

5. Department of Biochemistry Emory University School of Medicine Atlanta GA

Funder

American Liver Foundation

American Heart Association

National Institute of Diabetes and Digestive and Kidney Diseases

Weill Cornell Medical College

School of Medicine, Emory University

Publisher

Wiley

Subject

Hepatology

Reference35 articles.

1. Triglyceride metabolism in the liver;Alves‐Bezerra M;Compr Physiol,2017

2. Acyl‐CoA metabolism and partitioning;Grevengoed TJ;Ann Rev Nutr,2014

3. Deactivating fatty acids: acyl‐CoA thioesterase‐mediated control of lipid metabolism;Tillander VE;Trends Endocrinol Metab,2017

4. Thioesterase superfamily member 2 (Them2)/acyl‐CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long‐chain fatty acyl‐CoAs;Wei J;Biochem J,2009

5. Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2;Kanno K;J BiolChem,2007

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