Case Study: An accelerated 8-day monoclonal antibody production process based on high seeding densities
Author:
Affiliation:
1. Bioprocess Development; Merck Research Laboratories, Merck & Co., Inc.; Rahway NJ 07065
Publisher
Wiley
Subject
Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/btpr.1719/fullpdf
Reference5 articles.
1. EASE vectors for rapid stable expression of recombinant antibodies;Aldrich;Biotechnol Prog,2003
2. Role of iron and sodium citrate in animal protein-free CHO cell culture medium on cell growth and monoclonal antibody production;Bai;Biotechnol Prog,2011
3. Enhanced production of monomeric interferon-beta by CHO cells through the control of culture conditions;Rodriguez;Biotechnol Prog,2005
4. Production of recombinant protein therapeutics in cultivated mammalian cells;Wurm;Nat Biotechnol,2004
5. Defining process design space for monoclonal antibody cell culture;Abu-Absi;Biotechnol Bioeng,2010
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