Involvement of TIGIT in Natural Killer Cell Exhaustion and Immune Escape in Patients and Mouse Model With Liver Echinococcus multilocularis Infection

Author:

Zhang Chuanshan12,Wang Hui12,Li Jing2,Hou Xinling12,Li Linghui1,Wang Wei12,Shi Yang12,Li Dewei2,Li Liang3,Zhao Zhibin4,Li Liang4,Aji Tuerganaili5,Lin Renyong3,Shao Yingmei5,Vuitton Dominique A.6,Tian Zhigang78,Sun Haoyu78,Wen Hao1

Affiliation:

1. State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases in Central Asia Clinical Medicine Institute Xinjiang Medical UniversityThe First Affiliated Hospital of Xinjiang Medical University Urumqi China

2. Basic Medical CollegeXinjiang Medical University Urumqi China

3. Xinjiang Key Laboratory of Echinococcosis Clinical Medicine Institute WHO Collaborating Centre for Prevention and Case Management of Echinococcosis The First Affiliated Hospital of Xinjiang Medical University Urumqi China

4. Chronic Disease Laboratory Institutes for Life Sciences and School of Medicine South China University of Technology Guangzhou China

5. Department of Hepatic Hydatid and Hepatobiliary Surgery, Digestive and Vascular Surgery Centre The First Affiliated Hospital of Xinjiang Medical University Urumqi China

6. WHO Collaborating Centre for the Prevention and Treatment of Human Echinococcosis Department of Parasitology University Bourgogne Franche‐Comté (EA 3181) and University Hospital Besançon France

7. Hefei National Laboratory for Physical Sciences at Microscale The CAS Key Laboratory of Innate Immunity and Chronic Diseases School of Basic Medical Sciences Division of Life Sciences and Medicine University of Science and Technology of China Hefei China

8. Institute of Immunology University of Science and Technology of China Hefei China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Hepatology

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