Evaluation of urinary ribonucleoside profiling for clinical biomarker discovery using constant neutral loss scanning liquid chromatography/tandem mass spectrometry

Author:

Teichert Friederike1,Winkler Swantje1,Keun Hector C.2,Steward William P.1,Gescher Andreas J.1,Farmer Peter B.1,Singh Rajinder1

Affiliation:

1. Cancer Biomarkers and Prevention Group, Biocentre, Department of Cancer Studies and Molecular Medicine; University of Leicester; University Road; Leicester; LE1 7RH; UK

2. Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine; Imperial College London; Sir Alexander Fleming Building, South Kensington; London; SW7 2AZ; UK

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference59 articles.

1. Possible use of urinary modified RNA metabolites in the measurement of RNA turnover in the human body;Sander;Hum. Nutr. Clin. Nutr.,1986

2. Altered RNA turnover in carcinogenesis: the diagnostic potential of modified base excretion;Marvel;Mol. Chem. Neuropathol.,1994

3. Urinary excretion of modifed nucleosides as biological marker of RNA turnover in patients with cancer and AIDS;Nakano;Clin. Chim. Acta,1993

4. Urinary excretion of modified nucleosides in patients with malignant mesothelioma;Fischbein;Cancer Res.,1983

5. Urinary nucleosides;Schram;Mass Spectrom. Rev.,1998

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