Nano‐therapeutics: The upcoming nanomedicine to treat cancer

Author:

Khan Hamda1,Shahab Uzma2,Alshammari Ahmed3,Alyahyawi Amjad R.45,Akasha Rihab6,Alharazi Talal6,Ahmad Rizwan1,Khanam Afreen7,Habib Safia1,Kaur Kirtanjot8,Ahmad Saheem6ORCID,Moinuddin 1

Affiliation:

1. Department of Biochemistry, Jawahar Lal Nehru Medical College Aligarh Muslim University Aligarh India

2. Department of Biochemistry King George Medical University Lucknow India

3. Department of Internal Medicine, College of Medicine University of Hail Ha'il Saudi Arabia

4. Department of Diagnostic Radiology, College of Applied Medical Science University of Hail Ha'il Saudi Arabia

5. Centre for Nuclear and Radiation Physics, Department of Physics University of Surrey Guildford UK

6. Department of Medical Laboratory Sciences, College of Applied Medical Sciences University of Hail Ha'il Saudi Arabia

7. Department of Biotechnology & Life Science, Institute of Biomedical Education & Research Mangalayatan University Aligarh India

8. University Centre for Research and Development Chandigarh University Mohali India

Abstract

AbstractNanotechnology is considered a successful approach for cancer diagnosis and treatment. Preferentially, cancer cell recognition and drug targeting via nano‐delivery system include the penetration of anticancer agents into the cell membrane to damage the cancer cell by protein modification, DNA oxidation, or mitochondrial dysfunction. The past research on nano‐delivery systems and their target has proven the beneficial achievement in a malignant tumor. Modern perceptions using inventive nanomaterials for cancer management have been offered by a multifunctional platform based on various nano‐carriers with the probability of imaging and cancer therapy simultaneously. Emerging nano‐delivery systems in cancer therapy still lack knowledge of the biological functions behind the interaction between nanoparticles and cancer cells. Since the potential of engineered nanoparticles addresses the various challenges, limiting the success of cancer therapy subsequently, it is a must to review the molecular targeting of a nano‐delivery system to enhance the therapeutic efficacy of cancer. This review focuses on using a nano‐delivery system, an imaging system, and encapsulated nanoparticles for cancer therapy.

Publisher

Wiley

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