Synthesis and identification of deschloroketamine metabolites in rats' urine and a quantification method for deschloroketamine and metabolites in rats' serum and brain tissue using liquid chromatography tandem mass spectrometry-Reference-Cited by-同舟云学术

Synthesis and identification of deschloroketamine metabolites in rats' urine and a quantification method for deschloroketamine and metabolites in rats' serum and brain tissue using liquid chromatography tandem mass spectrometry

Published:2020-01-15 Issue:3 Volume:12 Page:343-360
ISSN:1942-7603
Container-title:Drug Testing and Analysis
language:en
Short-container-title:Drug Test Anal

Author:

Hájková Kateřina¹²³,Jurásek Bronislav¹⁴⁵^ORCID,Čejka Jan⁶,Štefková Kristýna⁵,Páleníček Tomáš⁵⁷,Sýkora David²,Kuchař Martin¹⁴⁵^ORCID

Affiliation:

1. Forensic Laboratory of Biologically Active Substances UCT Prague Technická 5 Prague Czech Republic

2. Department of Analytical Chemistry UCT Prague Technická 5 Prague Czech Republic

3. Department of Brain Electrophysiology National Institute of Mental Health Topolová Klecany Czech Republic

4. Department of Chemistry of Natural Compounds UCT Prague Technická 5 Prague Czech Republic

5. Department of Experimental Neurobiology National Institute of Mental Health Topolová Klecany Czech Republic

6. Department of Solid State Chemistry UCT Prague Technická 5 Prague Czech Republic

7. 3^rd Faculty of Medicine Charles University in Prague Ruská Prague Czech Republic

Publisher

Wiley

Subject

Spectroscopy,Pharmaceutical Science,Environmental Chemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/dta.2726

Reference58 articles.

1. UNODC ‐ United Nations Office on Drugs and Crime.Understanding the synthetic drug market: the NPS factor. Vol. 19 Global Smart Update.2018.https://www.unodc.org/documents/scientific/Global_Smart_Update_2018_Vol.19.pdf. Accessed 3 April 2019.

2. UNODC ‐ United Nations Office on Drugs and Crime.World Drug Report 2018. Executive summary conclusions and policy implications.2018.https://www.unodc.org/wdr2018/prelaunch/WDR18_Booklet_1_EXSUM.pdf. Accessed 3 April 2019.

3. EMCDDA ‐ European Monitoring Centre for Drugs and Drug Addiction and Europol.EDND – European information system and database on new drugs. Early Warning System on NPS;2019.https://ednd.emcdda.europa.eu/html.cfm/index6553EN.html. Accessed 25 March 2019.

4. Targeted and non-targeted drug screening in whole blood by UHPLC-TOF-MS with data-independent acquisition

5. The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In Vivo and In Vitro Metabolic Fate and Urinary Detectability of Five Deschloroketamine Derivatives Studied by Means of Hyphenated Mass Spectrometry;Metabolites;2024-05-08

2. Characterization of extensive 2-fluorodeschloroketamine metabolism in pooled human liver microsomes, urine and hair from an addicted patient using high-resolution accurate mass spectrometry;Journal of Analytical Toxicology;2023-06-03

3. Comparative Analysis and Structure Identification of Oxidative Metabolites and Hydrogenation Metabolite Enantiomers for 2-Fluorodeschloroketamine;Journal of Analytical Toxicology;2023-03-22

4. Characterization of 3-Hydroxyeticyclidine (3-HO-PCE) Metabolism in Human Liver Microsomes and Biological Samples Using High-Resolution Mass Spectrometry;Metabolites;2023-03-16

5. Characterization of 17 unknown ketamine manufacturing by‐product impurities by UHPLC‐QTOF‐MS;Drug Testing and Analysis;2022-06-30