Rationale and design of the ABOARD project (A Personalized Medicine Approach for Alzheimer's Disease)

Author:

Dreves Maria A. E.12,van Harten Argonde C.123,Visser Leonie N. C.1456,Rhodius‐Meester Hanneke1278,Köhler Sebastian9,Kooistra Minke10,Papma Janne M.11,Honey Madison I. J.23,Blom Marco M.10,Smets Ellen M. A.45,de Vugt Marjolein E.9,Teunissen Charlotte E.23,van der Flier Wiesje M.1212,

Affiliation:

1. Alzheimer Center Amsterdam Neurology Amsterdam UMC location VUmc Vrije Universiteit Amsterdam Amsterdam the Netherlands

2. Amsterdam Neuroscience Amsterdam UMC location VUmc Vrije Universiteit Amsterdam Amsterdam the Netherlands

3. Neurochemistry Laboratory Department of Clinical Chemistry Vrije Universiteit Amsterdam Amsterdam the Netherlands

4. Department of Medical Psychology Amsterdam UMC location AMC University of Amsterdam Amsterdam the Netherlands

5. Amsterdam Public Health Research Institute Quality of Care Amsterdam UMC location AMC University of Amsterdam Amsterdam the Netherlands

6. Division of Clinical Geriatrics Center for Alzheimer Research Department of Neurobiology Care Sciences and Society Karolinska Institutet Stockholm Sweden

7. Department of Internal Medicine Geriatric Medicine section Vrije Universiteit Amsterdam Amsterdam the Netherlands

8. Department of Geriatric Medicine The Memory Clinic Oslo University Hospital Oslo Norway

9. Department of Psychiatry and Neuropsychology School for Mental Health and Neuroscience Maastricht University Maastricht the Netherlands

10. Alzheimer Nederland Amersfoort the Netherlands

11. Department of Neurology and Alzheimer Center Erasmus MC Erasmus MC University Medical Center Rotterdam the Netherlands

12. Department of Epidemiology and Data Science Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam Amsterdam the Netherlands

Abstract

AbstractThe key to stopping Alzheimer's disease (AD) lies in the pre‐dementia stages, with the goal to stop AD before dementia has started. We present the rationale and design of the ABOARD (A Personalized Medicine Approach for Alzheimer's Disease) project, which aims to invest in personalized medicine for AD. ABOARD is a Dutch public–private partnership of 32 partners, connecting stakeholders from a scientific, clinical, and societal perspective. The 5‐year project is structured into five work packages on (1) diagnosis, (2) prediction, (3) prevention, (4) patient‐orchestrated care, and (5) communication and dissemination. ABOARD functions as a network organization in which professionals interact cross‐sectorally. ABOARD has a strong junior training program “Juniors On Board.” Project results are shared with society through multiple communication resources. By including relevant partners and involving citizens at risk, patients, and their care partners, ABOARD builds toward a future with personalized medicine for AD.Highlights ABOARD (A Personalized Medicine Approach for Alzheimer's Disease) is a public–private research project executed by 32 partners that functions as a network organization. Together, the project partners build toward a future with personalized medicine for Alzheimer's disease. Although ABOARD is a Dutch consortium, it has international relevance. ABOARD improves diagnosis, prediction, prevention, and patient‐orchestrated care.

Publisher

Wiley

Subject

Psychiatry and Mental health,Neurology (clinical)

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