A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease
Author:
Affiliation:
1. Alzheimer's Research UK; Cambridge
2. Reta Lila Weston Laboratories; London
3. Department of Molecular Neuroscience; University College London; London United Kingdom
Funder
Wellcome Trust
Publisher
Wiley
Subject
Clinical Neurology,Neurology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/ana.24188/fullpdf
Reference132 articles.
1. About a peculiar disease of the cerebral cortex;Alzheimer;Centralblatt für Nervenheilkunde Psychiatrie,1907
2. The molecular pathology of Alzheimer's disease;Selkoe;Neuron,1991
3. Alzheimer's disease: the amyloid cascade hypothesis;Hardy;Science,1992
4. Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein;Glenner;Biochem Biophys Res Commun,1984
5. Prevalence of Alzheimer's disease and vascular dementia: association with education. The Rotterdam study;Ott;BMJ,1995
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