A case report of hypokalemic periodic muscular weakness secondary to Sjögren's syndrome with distal renal tubular acidosis

Author:

Iqbal Marhaba1,Khan Qaisar Ali1ORCID,Belay Naod F.2ORCID,Azeem Moheem3,Amatul‐Hadi Faiza4,Afzal Muhammad5,Pande Harshawardhan6,Shah Syed Yasir1,Ahmed Rahma7,Iram Sumaira8,Verma Ravina5

Affiliation:

1. Khyber Teaching Hospital MTI KTH Peshawar Pakistan

2. Michigan State University East Lansing Michigan USA

3. Aga Khan University Karachi Pakistan

4. Mercer University School of Medicine Macon Georgia USA

5. St. George's University True Blue Grenada

6. Saint Louis University St. Louis Missouri USA

7. Kennesaw State University Kennesaw Georgia USA

8. Sultan Qaboos University Muscat Oman

Abstract

Key Clinical MessageAn underlying autoimmune condition should be suspected in patients who presented with periodic muscular weakness secondary to distal RTA that leads to hypokalemia because distal RTA is commonly associated with autoimmune disorders such as Sjögren's syndrome.AbstractA 22‐year‐old female presented with a sudden onset of bilateral weakness in both upper and lower limbs. The patient had a history of muscular weakness secondary to hypokalemia and dryness of the eyes for the last 3 years. Laboratory investigations revealed decreased potassium and metabolic acidosis. Further investigations confirmed distal renal tubular acidosis (RTA) and Sjögren's syndrome. A diagnosis of distal RTA secondary to Sjögren's syndrome was made. Her potassium levels were replaced, and she was discharged with oral potassium supplements, steroids, and artificial tears.

Publisher

Wiley

Subject

General Medicine

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