Compendium of proteins containing segments that exhibit<scp>zero‐tolerance</scp>to amino acid variation in humans-Reference-Cited by-同舟云学术

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Compendium of proteins containing segments that exhibitzero‐toleranceto amino acid variation in humans

Published:2022-08-18 Issue:9 Volume:31 Page:
ISSN:0961-8368
Container-title:Protein Science
language:en
Short-container-title:Protein Science

Author:

Sanders Adam L.¹,Hermanson Jake N.²,Samuels David C.³,Plate Lars⁴^ORCID,Sanders Charles R.¹⁵⁶^ORCID

Affiliation:

1. Department of Biochemistry Vanderbilt University School of Medicine—Basic Sciences Nashville Tennessee USA

2. Quantitative Chemical and Physical Biology Graduate Program Vanderbilt University School of Medicine—Basic Sciences Nashville Tennessee USA

3. Department of Molecular Physiology and Biophysics Vanderbilt University School of Medicine Nashville Tennessee USA

4. Departments of Chemistry and Biological Sciences Vanderbilt University Nashville Tennessee USA

5. Center for Structural Biology Vanderbilt University School of Medicine—Basic Sciences Nashville Tennessee USA

6. Department of Medicine Vanderbilt University School of Medicine Nashville Tennessee USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pro.4408

Reference36 articles.

1. MTR-Viewer: identifying regions within genes under purifying selection

2. Optimizing genomic medicine in epilepsy through a gene-customized approach to missense variant interpretation

3. Three-dimensional missense tolerance ratio analysis

4. LoFtool: A gene intolerance score based on loss‐of‐function variants in 60 706 individuals;Fadista J;Bioinformatics,2017

5. A map of constrained coding regions in the human genome

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