Unlike CD4+ T-cell help, CD28 costimulation is necessary for effective primary CD8+ T-cell influenza-specific immunity

Author:

Seah Shirley G.K.,Carrington Emma M.1,Ng Wy C.2,Belz Gabrielle T.1,Brady Jamie L.1,Sutherland Robyn M.1,Hancock Manuela S.1,La Gruta Nicole L.2,Brown Lorena E.2,Turner Stephen J.2,Zhan Yifan1,Lew Andrew M.1

Affiliation:

1. Walter and Eliza Hall Institute of Medical Research; 1G Royal Parade; Parkville; Australia

2. Department of Microbiology and Immunology; University of Melbourne; Parkville; Australia

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference84 articles.

1. Effector CD4+ and CD8+ T-cell mechanisms in the control of respiratory virus infections;Doherty;Immunol. Rev.,1997

2. Help for cytotoxic-T-cell responses is mediated by CD40 signalling;Bennett;Nature,1998

3. A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell;Ridge;Nature,1998

4. CD40-CD40Ligand interactions and their role in cytotoxic T lymphocyte priming and anti-tumor immunity;Toes;Semin. Immunol.,1998

5. Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease;Buhlmann;J. Immunol.,1999

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