Antigen amount dictates CD8+T-cell exhaustion during chronic viral infection irrespective of the type of antigen presenting cell
Author:
Affiliation:
1. Institute of Microbiology; ETH Zurich; Zurich; Switzerland
2. Institute for Immunology; Ludwig-Maximilian-University; Munich; Germany
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201142275/fullpdf
Reference58 articles.
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3. Sustained dysfunction of antiviral CD8+T lymphocytes after infection with hepatitis C virus;Gruener;J. Virol.,2001
4. Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape;Sewell;Stem Cells,2000
5. Functional discrepancies in HIV-specific CD8+T-lymphocyte populations are related to plasma virus load;Oxenius;J. Clin. Immunol.,2002
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