Loss of central and peripheral CD8+T-cell tolerance to HFE in mouse models of human familial hemochromatosis-Reference-Cited by-同舟云学术

Loss of central and peripheral CD8+T-cell tolerance to HFE in mouse models of human familial hemochromatosis

Published:2012-04 Issue:4 Volume:42 Page:851-862
ISSN:0014-2980
Container-title:European Journal of Immunology
language:en
Short-container-title:Eur. J. Immunol.

Author:

Boucherma Rachid,Kridane-Miledi Hédia¹,Langa Vives Francina²,Vauchy Charline³,Borg Christophe,Kleinclauss François,Fiette Laurence⁴,Tiberghien Pierre³,Lemonnier François A.¹,Rohrlich Pierre S.,Huetz François¹

Affiliation:

1. Unité d’Immunité Cellulaire Antivirale; Département d’Immunologie; Institut Pasteur; Paris; France

2. Centre d’Ingénierie Génétique Murine; Département de Biologie du Développement; Institut Pasteur; Paris; France

3. Inserm UMR 645 -IFR133; Université de Franche-Comté; EFS BFC; Besançon; France

4. Unité d’Histopathologie Humaine et Modèles Animaux; Département Infection et Epidémiologie; Institut Pasteur; Paris; France

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/eji.201141664/fullpdf

Reference44 articles.

1. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis;Feder;Nat. Genet,1996

2. The C282Y mutation causing hereditary hemochromatosis does not produce a null allele;Levy;Blood,1999

3. Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor;Lebron;Cell,1998

4. Direct recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function;Rohrlich;Proc. Natl. Acad. Sci. USA,2005

5. Development of CD4+CD8 + thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway;Guidos;J. Exp. Med,1995

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4. The WT hemochromatosis protein HFE inhibits CD8+T-lymphocyte activation;European Journal of Immunology;2014-03-20

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