Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia-The Influence of Thiopurine Methyltransferase Genotypes-Reference-Cited by-同舟云学术

Incorporation of 6-Thioguanine Nucleotides into DNA During Maintenance Therapy of Childhood Acute Lymphoblastic Leukemia-The Influence of Thiopurine Methyltransferase Genotypes

Published:2013-04-15 Issue:6 Volume:53 Page:670-674
ISSN:0091-2700
Container-title:The Journal of Clinical Pharmacology
language:en
Short-container-title:The Journal of Clinical Pharmacology

Author:

Ebbesen Maria S.¹,Nersting Jacob¹,Jacobsen Jack H.¹,Frandsen Thomas L.¹,Vettenranta Kim²,Abramsson Jonas³,Wesenberg Finn⁴,Schmiegelow Kjeld

Affiliation:

1. Department of Pediatrics and Adolescent Medicine; The University Hospital Rigshospitalet; Copenhagen; Denmark

2. Division of Hematology-Oncology, Department of Pediatrics; University of Tampere; Tampere; Finland

3. Department of Pediatrics; Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg; Gothenburg; Sweden

4. Department of Pediatrics; Oslo University Hospital/Medical Faculty, University of Oslo; Oslo; Norway

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcph.81/fullpdf

Reference27 articles.

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3. Thiopurines: factors influencing toxicity and response;Fotoohi;Biochem Pharmacol,2010

4. Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia-results from the NOPHO ALL-92 study;Schmiegelow;Blood,2009

5. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity;Lennard;Br J Clin Pharmacol,1997

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