Biomarker‐based assessment of collagen cross‐linking identifies patients at risk of heart failure more likely to benefit from spironolactone effects on left atrial remodelling. Insights from the HOMAGE clinical trial

Author:

Ravassa Susana12,López Begoña12,Ferreira João Pedro3,Girerd Nicolas3,Bozec Erwan3,Pellicori Pierpaolo4,Mariottoni Beatrice5,Cosmi Franco5,Hazebroek Mark6,Verdonschot Job A.J.6,Cuthbert Joe7,Petutschnigg Johannes8,Moreno María U.12,Heymans Stephane6,Staessen Jan A.910,Pieske Burkert811,Edelmann Frank8,Clark Andrew L.7,Cleland John G.F.4,Zannad Faiez3,Díez Javier1212,González Arantxa12,

Affiliation:

1. Program of Cardiovascular Diseases, CIMA Universidad de Navarra and IdiSNA Pamplona Spain

2. CIBERCV, Carlos III Institute of Health Madrid Spain

3. Université de Lorraine, Inserm, Centre d'Investigation Clinique Plurithématique 1433, U1116, CHRU de Nancy, F‐CRIN INI‐CRCT Nancy France

4. Robertson Centre for Biostatistics, Institute of Health and Wellbeing University of Glasgow, Glasgow Royal Infirmary Glasgow UK

5. Department of Cardiology Cortona Hospital Arezzo Italy

6. Department of Cardiology Maastricht University Medical Center Maastricht The Netherlands

7. Department of Cardiology University of Hull, Castle Hill Hospital Cottingham UK

8. Department of Internal Medicine and Cardiology Campus Virchow Klinikum Charité University Medicine Berlin and German Centre for Cardiovascular Research (DZHK), Partner Site Berlin Berlin Germany

9. Non‐Profit Research Institute Alliance for the Promotion of Preventive Medicine, Mechelen (APPREMED) Mechelen Belgium

10. Biomedical Sciences Group, Faculty of Medicine University of Leuven Leuven Belgium

11. Berlin Institute of Health Berlin Germany

12. Departments of Nephrology and Cardiology Clínica Universidad de Navarra Pamplona Spain

Funder

British Heart Foundation

European Commission

Instituto de Salud Carlos III

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine

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