Cartilage regeneration is related to superior mid‐term patient‐reported outcomes after open‐wedge high tibial osteotomy

Author:

Tsushima Takahiro1ORCID,Sasaki Eiji1ORCID,Sakamoto Yukiko1,Kimura Yuka1,Tsuda Eiichi2,Ishibashi Yasuyuki1

Affiliation:

1. Department of Orthopaedic Surgery Hirosaki University, Graduate School of Medicine Hirosaki Japan

2. Department of Rehabilitation Medicine Hirosaki University, Graduate School of Medicine Hirosaki Japan

Abstract

AbstractPurposeMedial open‐wedge high tibial osteotomy (OWHTO) is related to cartilage improvement in the medial compartment. This study aimed to evaluate factors associated with cartilage improvement and patient‐reported outcomes (PRO) after OWHTO. It was hypothesised that cartilage improvement is associated with favourable PRO.MethodsThis retrospective study included 94 patients who underwent OWHTO. The mean follow‐up period was 5 years. The weight‐bearing line ratio (WBLR) was defined as the ratio of the distance from the medial tibial edge to the tibial insertion of the weight‐bearing line and the tibial width. The International Cartilage Research Society grade evaluated the medial femoral condyle (MFC) and medial tibial plateau (MTP) at initial and second‐look arthroscopy, and cartilage improvement after OWHTO was assessed. Postoperative knee injury and osteoarthritis outcome scores (KOOS) were compared between the groups with improved and non‐improved cartilage. Additionally, factors related to cartilage improvement and postoperative KOOS scores were analysed.ResultsRegarding the MFC, KOOS pain, symptoms, activities of daily living (ADL) and quality of life (QOL) were significantly higher in the cartilage‐improved group than in the non‐improved group (p = 0.012, 0.003, 0.001, 0.006), and cartilage improvement was significantly related to KOOS pain, ADL and QOL (p = 0.021, 0.039, 0.013). In addition, the postoperative WBLR was associated with cartilage improvement, with a cutoff value of 54.0% (p = 0.046). Regarding the MTP, KOOS ADL and QOL (p = 0.026, 0.022) were significantly higher in the cartilage‐improved group than in the nonimproved group. Body mass index (BMI) was significantly related to the postoperative QOL (p = 0.018) and associated with cartilage improvement, with a cutoff value of 25.9 kg/m2 (p = 0.002).ConclusionA postoperative WBLR greater than 54.0% and a preoperative BMI below 25.9 kg/m2 were associated with cartilage improvement, positively impacting PRO after OWHTO.Level of EvidenceLevel III, retrospective comparative study.

Publisher

Wiley

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