Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis

Author:

Ovadia Caroline1ORCID,Perdones‐Montero Alvaro2,Spagou Konstantina2,Smith Ann3,Sarafian Magali H.2,Gomez‐Romero Maria2,Bellafante Elena1,Clarke Louise C.D.1,Sadiq Fouzia4,Nikolova Vanya1,Mitchell Alice1,Dixon Peter H.1,Santa‐Pinter Natalie1,Wahlström Annika5,Abu‐Hayyeh Shadi1,Walters Julian R.F.4,Marschall Hanns‐Ulrich5,Holmes Elaine2,Marchesi Julian R.36,Williamson Catherine1

Affiliation:

1. Division of Women and Children's Health King's College London London United Kingdom

2. Section of Biomolecular Medicine, Division of Computational & Systems Medicine, Department of Surgery & Cancer, Faculty of Medicine Imperial College London London United Kingdom

3. School of Biosciences Cardiff University Cardiff United Kingdom

4. Division of Digestive Diseases Hammersmith Hospital, Imperial College London London United Kingdom

5. Institute of Medicine, Department of Molecular and Clinical Medicine and Wallenberg Laboratory University of Gothenburg Gothenburg Sweden

6. Centre for Digestive and Gut Health, Department of Surgery and Cancer Imperial College London London United Kingdom

Funder

Wellcome Trust

Tommy's

Guy's and St Thomas' NHS Foundation Trust

King’s College London

Imperial College Healthcare NHS Trust

Genesis Research Trust

Publisher

Wiley

Subject

Hepatology

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