Self‐Generated Displacement Current of Triboelectric Nanogenerator for Cancer Therapy: Theory and Application-Reference-Cited by-同舟云学术

Self‐Generated Displacement Current of Triboelectric Nanogenerator for Cancer Therapy: Theory and Application

Published:2023-11-27 Issue:2 Volume:9 Page:
ISSN:2365-709X
Container-title:Advanced Materials Technologies
language:en
Short-container-title:Adv Materials Technologies

Author:

Chen Meihua¹,Cui Xin¹,Zhang Yaming¹,Zou Pingjin¹,Xiao Ling¹,Kang Mengzhe¹,Chen Junyang²,Ren Junjin¹,Fang Zengyi¹,Li Lijie³,Lang Jinyi¹,Zhang Yan¹³⁴^ORCID,Wang Zhong Lin⁴⁵

Affiliation:

1. Department of Radiation Oncology Radiation Oncology Key Laboratory of Sichuan Province Sichuan Clinical Research Center for Cancer Sichuan Cancer Hospital & Institute Sichuan Cancer Center School of Physics Affiliated Cancer Hospital of University of Electronic Science and Technology of China Chengdu 610054 China

2. School of Clinical Medicine Chengdu University of Traditional Chinese Medicine Chendu 610072 China

3. College of Engineering Swansea University Swansea SA1 8EN UK

4. Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing 100083 China

5. College of Nanoscience and Technology University of Chinese Academy of Sciences Beijing 100049 China

Abstract

AbstractWearable and implantable triboelectric nanogenerators (TENGs) convert mechanical energy to electricity in the daily movements of the human body. Self‐generated dynamic electric field or displacement current of TENGs can operate from micrometers to centimeters, which offers a key technology for TENG‐based therapy systems for precision medicine on both tissues and cells. TENGs have low‐current and high‐voltage properties, which reduce damage to normal tissues, and kill rapidly dividing cancer cells. In this work, the dynamic electric field from TENG directly inhibits the cellular proliferation behavior of cancer cells. The work paves a new way for the self‐generated electric field of TENG for cancer therapy.

Funder

Science and Technology Department of Sichuan Province

Central University Basic Research Fund of China

Publisher

Wiley

Subject

Industrial and Manufacturing Engineering,Mechanics of Materials,General Materials Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/admt.202301225

Reference86 articles.

1. Tumor-treating fields induce autophagy by blocking the Akt2/miR29b axis in glioblastoma cells

2. Disruption of Cancer Cell Replication by Alternating Electric Fields

3. Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors

4. Chemotherapeutic treatment efficacy and sensitivity are increased by adjuvant alternating electric fields (TTFields)

5. Post Hoc Analyses of Intention-to-Treat Population in Phase III Comparison of NovoTTF-100A™ System Versus Best Physician’s Choice Chemotherapy