Wearable Perovskite Films for On‐Line Monitoring of Radiotracers in Nuclear Medicine

Author:

Basiricò Laura12ORCID,Verdi Matteo12ORCID,Ciavatti Andrea12ORCID,Piergallini Lorenzo3,Grassi Elisa3ORCID,Fioroni Federica3ORCID,Margotti Lorenzo1ORCID,Tosi Nicolò2ORCID,Cicero Valentina2ORCID,Montanari Alessandro2ORCID,Iori Mauro3ORCID,Fraboni Beatrice12ORCID

Affiliation:

1. Department of Physics and Astronomy University of Bologna Viale Berti Pichat 6/2 Bologna 40127 Italy

2. National Institute for Nuclear Physics—INFN section of Bologna Viale Berti‐Pichat 6/2 Bologna 40127 Italy

3. Medical Physics Unit Azienda USL‐IRCCS di Reggio Emilia Reggio Emilia 42123 Italy

Abstract

AbstractOn‐line in situ monitoring of radiation emitted by radiotracers during intravenous injection is of crucial importance for the safety of patients and personnel involved in nuclear medicine treatments and analysis. The aim of this work is to assess wearable perovskite ionizing radiation detectors for such application. With this purpose pixelated direct detector based on thin films of 2D layered perovskite PEA2PbBr4 are tested for the monitoring of gamma‐rays emitted by 18F radiopharmaceutical under different experimental conditions. The wearable detector is here demonstrated being able to detect in real‐time the gamma‐rays emitted by annihilation of 18F radiotracer. Its reliability is assessed by 18F half‐life measurement with a maximum accuracy deviation within 8%. The detector also successes in its validation for the foreseen application, demonstrating able to monitor in real‐time the whole injection process and extravasation event.

Funder

Regione Emilia-Romagna

Ministero della Salute

Publisher

Wiley

Reference29 articles.

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