Affiliation:
1. School of Biomedical Engineering Sun Yat‐sen University Shenzhen 518107 China
2. State Key Laboratory of Optoelectronic Materials and Technologies Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology Sun Yat‐sen University Guangzhou 510006 China
3. The Laboratory for Advanced Functional/Medicinal Polymers & Smart Drug Delivery Technologies The Wolfson Faculty of Chemical Engineering Technion‐Israel Institute of Technology Haifa 3200003 Israel
4. Department of Biomedical Engineering City University of Hong Kong Hong Kong 999077 China
Abstract
AbstractCardiovascular diseases, which cause ≈10 million deaths annually, underscored the importance of effective blood pressure (BP) monitoring. Traditional devices, however, faced limitations that hindered the adoption of continuous monitoring technologies. Flexible triboelectric nanogenerator (TENG) sensors, known for their rapid response, high sensitivity, and cost‐effectiveness, presented a promising alternative. Enhancing their ability to capture weak biological signals can be achieved by optimizing the material's friction coefficient and expanding the effective contact area. In this work, a flexible microcolumn‐based TENG sensor with high sensitivity is developed by fabricating microcolumns of carbon nanotube/polydimethylsiloxane (CNT/PDMS) composites on porous polyethylene terephthalate (PET) membranes using template etching and integrating these with fluorinated ethylene propylene (FEP) film. With the enhancement of microcolumn structure, the sensor possessed high sensitivity and good response, enabling it to effectively and accurately detect subtle physiological changes such as radial pulses and fingertip pulsations, with pulse wave signals highly consistent with the interbeat intervals of electrocardiograms. Leveraging these capabilities, a non‐invasive dynamic BP monitoring system capable of continuous beat‐to‐beat BP monitoring is developed. This advancement enables easier and more effective health monitoring, empowering individuals to better manage their health and improve personalized medical care.
Funder
National Natural Science Foundation of China
Basic and Applied Basic Research Foundation of Guangdong Province
National Key Research and Development Program of China
China Postdoctoral Science Foundation