From the kitchen to the medicine cabinet: Examples of functional herbs and spices

Author:

Gura Kathleen12ORCID,Duro Debora34,Pai Nikhil56,Sandell Angela7,Sankararaman Senthilkumar89,Quiros‐Tejeira Rubén10,Herdes Rachel11,Deas Jessica12,Wang Linda13

Affiliation:

1. Department of Pharmacy/Division of Gastroenterology Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA

2. Department of Pediatrics Harvard Medical School Boston Massachusetts USA

3. Pediatric Gastroenterology, Hepatology and Nutrition at Salah Foundation Children Hospital at Broward Health Fort Lauderdale Florida USA

4. Clinical Pediatrics at NOVA Southeastern University, Fort Lauderdale FL and Florida International University (FIU) Miami Florida USA

5. Department of Pediatrics, Faculty of Health Sciences McMaster University Hamilton Ontario Canada

6. Division of Pediatric Gastroenterology & Nutrition, McMaster Children's Hospital Hamilton Ontario Canada

7. Department of Pediatric Gastroenterology Hepatology, and Nutrition at University of Rochester Medical Center Rochester New York USA

8. Division of Pediatric Gastroenterology Hepatology & Nutrition. UH Rainbow Babies & Children's Hospital Cleveland Ohio USA

9. Case Western Reserve University Cleveland Ohio USA

10. Pediatric Gatroentoerology, Hepatology & Nutrition University of Nebraska Medical Center Omaha Nebraska USA

11. Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition Stanford University School of Medicine Stanford California USA

12. Division of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles Los Angeles California USA

13. Keck School of Medicine University of Southern California Los Angeles California USA

Abstract

AbstractIn many cultures, “food as medicine” has existed for centuries as the foundation of health. It is a practice built on the knowledge that food and diet play important roles in disease prevention and management. Foods possessing therapeutic properties are often referred to as functional foods. Many herbs and spices contain numerous nutritional and non‐nutritional components that can interact with pharmacologically relevant receptors, either directly or indirectly via their metabolites, to regulate cellular biochemical processes. Although opinions are changing, the concept of food as a therapeutic intervention goes against conventional Western medicine. To provide guidance to clinicians interested in using these products, members of the Food as Medicine working group of the Nutrition Committee NASPGHAN, as part of a two‐part review series, have identified frequently used foods, supplements, herbs, and spices that are utilized for therapeutic intent and have created summaries of commonly used indications, doses, and caveats. In this review, the focus is the use of select herbs and spices for medicinal purposes. Gaps in our knowledge in how to effectively use these agents in pediatric patients are discussed. Evidence supporting their use for management of gastrointestinal conditions, especially in the pediatric population, is provided when available. Circumstances in clinical settings and patient indications may require actions different from those recommended in this review and professional judgment should prevail.

Publisher

Wiley

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