Prevalence of epilepsy in Morocco: A population‐based study

Author:

Souirti Zouhayr12ORCID,Hmidani Mohammed1,Lamkadddem Abdelaziz1,Khabbach Kawtar3,Belakhdar Salma4,Charkani Doae5,Mhandez Tlemcani Driss2,Lahmadi Nabila2,El Akramine Maroua2,Erriouiche Samira2,Berrada Asmae2,Ahniba Asmae2,Omari Mohammed6,El Fakir Samira6,Tachfouti Nabil6,Rafai Mohammed Abdoh7,Chahid Imane8,Meriam Bentahar9,Jilla Mariam10,Ghaname Aayad11,Benmansour Youssef12,Filali Zegzouti Younes13,Kissani Najib14ORCID,Lakhdar Abdelhakim15,Belfkih Rachid16,Aggouri Mohamed16,Ouazzani Reda17,Chahidi Abderrahmane1,Janati Idrissi Abdelkrim1ORCID

Affiliation:

1. Clinical Neurosciences Laboratory, Faculty of Medicine and Pharmacy Sidi Mohamed Ben Abdellah University Fez Morocco

2. Neurology Center Hassan II University Hospital in Fez Fez Morocco

3. Mohamed VI Hospital Center, Faculty of Medicine and Pharmacy – Tangier Abdelmalek Essaadi University Tanger Morocco

4. Ibn Rochd University Hospital Center, Faculty of Medicine and Pharmacy Hassan II University of Casablanca Casablanca Morocco

5. Outpatient Consultations Center Hassan II University Hospital in Fez Fez Morocco

6. Clinical Research and Community Health Laboratory, Faculty of Medicine and Pharmacy, Epidemiology Sidi Mohamed Ben Abdellah University Fez Morocco

7. Department of Neurology and Clinical Neurophysiological Explorations, Faculty of Medicine and Pharmacy, Ibn Rochd Hospital Hassan II University of Casablanca Casablanca Morocco

8. Department of Pediatric, Faculty of Medicine and Pharmacy, Centre Hospitalier Ibn Rochd Hassan II University of Casablanca Casablanca Morocco

9. Faculty of Medicine Laayoune, Hôpital Moulay Hassane Ben Mehdi Ibn Zouhr University Laayoune Morocco

10. Provincial Hospital Center Abdelmalek Essaadi University Al Hoceima Morocco

11. Department of Pediatrics, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital Mohammed I University Oujda Oujda Morocco

12. Hôpital Provincial Hassan II Settat Morocco

13. BASE Laboratory, FSM‐FSTE Moulay Ismail University of Meknes Meknes Morocco

14. Department of Neurology, Marrakech Faculty of Medicine and Pharmacy University Hospital Mohamed VI Marrakech Morocco

15. Department of Neurosurgery, Faculty of Medicine and Pharmacy, Ibn Rochd Hospital Hassan II University of Casablanca Casablanca Morocco

16. Mohammed VI Hospital Center, Department of Neurology, Faculty of Medicine and Pharmacy – Tangier Abdelmalek Essaadi University Tangier Morocco

17. Department of Clinical Neurophysiology, Faculty of Medicine and Pharmacy of Rabat, Avicenne Hospital Mohammed V University of Rabat Rabat Morocco

Abstract

AbstractObjectiveIn Morocco, there was a lack of data related to the epidemiology of epilepsy. This data serves as a useful basis for the development of any national intervention or action program against epilepsy in Morocco. Through this study, we aimed to estimate the active and lifetime prevalence of epilepsy in Morocco.MethodsWe collected data from eight out of 12 Moroccan regions in two steps: In the screening step, we first used a nationwide telephone diagnosis questionnaire and in the second stage, a team of physicians under the direction of an epileptologist conducted a confirmative survey for suspected cases. We fixed the confidence interval at α = 5% and the precision at 0.02.ResultsUp to 3184 responded positively to our invitation to participate in this study and were able to answer the questions of the first diagnostic questionnaire. In the diagnostic phase, physicians in neurology reinterviewed all 86 suspected cases using a confirmative diagnosis questionnaire, and 63 persons were confirmed as having lifetime epilepsy and 56 with active epilepsy. The mean age (Mean ± SD) of persons with epilepsy was 35.53 years (±21.36). The prevalence of lifetime and active epilepsy were 19.8 (19.6–20.0) and 17.6 (17.5–17.8) per 1000 (95% confidence interval), respectively.SignificanceThis is the first study to estimate the active and lifetime prevalence of epilepsy in Morocco according to the international recommendations of the ILAE. The prevalence of lifetime and active epilepsy were 19.8 (15–24.6) and 17.6 (13.3–22.8) per 1000, respectively. We included both children and elderly subjects. The rates of active and lifetime population epilepsy prevalence in Morocco ranged between Asian and sub‐Saharan Africa low‐ and middle‐income countries.

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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