Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation

Author:

Auclair Jared R.1234,Salisbury Joseph P.12,Johnson Joshua L.34,Petsko Gregory A.34,Ringe Dagmar34,Bosco Daryl A.56,Agar Nathalie Y. R.78,Santagata Sandro9,Durham Heather D.10,Agar Jeffrey N.12

Affiliation:

1. Department of Chemistry and Chemical Biology; Barnett Institute; Northeastern University; Boston MA USA

2. Department of Pharmaceutical Sciences; Northeastern University; Boston MA USA

3. Department of Biochemistry; Rosenstiel Basic Medical Sciences Research Center; Brandeis University; Waltham MA USA

4. Department of Chemistry; Rosenstiel Basic Medical Sciences Research Center; Brandeis University; Waltham MA USA

5. Department of Neurology; University of Massachusetts Medical School; Worcester MA USA

6. Department of Biochemistry and Molecular Pharmacology; University of Massachusetts Medical School; Worcester MA USA

7. Department of Neurosurgery; Brigham and Women's Hospital; Harvard Medical School; Boston MA USA

8. Department of Radiology; Brigham and Women's Hospital; Harvard Medical School; Boston MA USA

9. Department of Pathology; Brigham and Women's Hospital; Harvard Medical School; Boston MA USA

10. Department of Neurology and Neurosurgery; Montreal Neurological Institute; McGill University Montreal; Quebec Canada

Funder

National Institutes of Health

ALS Therapy Alliance/CVS Pharmacy

Fidelity Biosciences Research Initiative

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

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