Tyrosine 656 in topoisomerase IIβ is important for the catalytic activity of the enzyme: Identification based on artifactual +80-Da modification at this site

Author:

Grozav Adrian G.,Willard Belinda B.,Kozuki Toshiyuki,Chikamori Kenichi,Micluta Marius A.,Petrescu Andrei-Jose,Kinter Michael,Ganapathi Ram,Ganapathi Mahrukh K.

Funder

United States Public Health Service Grant

CNCSIS

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference50 articles.

1. DNA topoisomerases;Wang;Annu. Rev. Biochem.,1996

2. Cellular roles of DNA topoisomerases: a molecular perspective;Wang;Nat. Rev. Mol. Cell. Biol.,2002

3. Culprit and victim-DNA topoisomerase II;Kellner;Lancet Oncol.,2002

4. Topoisomerase IIα and topoisomerase IIβ genes: characterization and mapping to human chromosomes 17 and 3, respectively;Tan;Cancer Res.,1992

5. Structural organization of the human TOP2A and TOP2B genes;Lang;Gene,1998

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