Proteomics and Network Analyses Reveal Inhibition of Akt-mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan-Reference-Cited by-同舟云学术

Proteomics and Network Analyses Reveal Inhibition of Akt-mTOR Signaling in CD4+ T Cells by Mycobacterium tuberculosis Mannose-Capped Lipoarabinomannan

Published:2017-11 Issue:22 Volume:17 Page:1700233
ISSN:1615-9853
Container-title:PROTEOMICS
language:en
Short-container-title:Proteomics

Author:

Karim Ahmad F.¹²,Sande Obondo J.¹,Tomechko Sara E.³,Ding Xuedong¹,Li Ming³,Maxwell Sean³,Ewing Rob M.⁴,Harding Clifford V.²⁵,Rojas Roxana E.²,Chance Mark R.³⁶,Boom W. Henry¹²

Affiliation:

1. Department of Medicine; University Hospitals Cleveland Medical Center; Case Western Reserve University; Cleveland OH USA

2. Department of Molecular Biology & Microbiology; Case Western Reserve University; Cleveland OH USA

3. Center for Proteomics & Bioinformatics; Case Western Reserve University; Cleveland OH USA

4. Centre for Biological Sciences; University of Southampton; Southampton UK

5. Department of Pathology; University Hospitals Cleveland Medical Center; Case Western Reserve University; Cleveland OH USA

6. Department of Nutrition; School of Medicine; Case Western Reserve University; Cleveland OH USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference57 articles.

1. T cell mediated immunity to Mycobacterium tuberculosis

2. The Mycobacterium tuberculosis 19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Regulated HLA-DR and FcγR1 on Human Macrophages through Toll-Like Receptor 2

3. Mycobacterium tuberculosisLprG (Rv1411c): A Novel TLR-2 Ligand That Inhibits Human Macrophage Class II MHC Antigen Processing

4. Mycobacterium tuberculosisLprA Is a Lipoprotein Agonist of TLR2 That Regulates Innate Immunity and APC Function

5. Phosphatidylinositol Mannoside fromMycobacterium tuberculosisBinds α5β1Integrin (VLA-5) on CD4+T Cells and Induces Adhesion to Fibronectin

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