Large-scale multiplex absolute protein quantification of drug-metabolizing enzymes and transporters in human intestine, liver, and kidney microsomes by SWATH-MS: Comparison with MRM/SRM and HR-MRM/PRM-Reference-Cited by-同舟云学术

Large-scale multiplex absolute protein quantification of drug-metabolizing enzymes and transporters in human intestine, liver, and kidney microsomes by SWATH-MS: Comparison with MRM/SRM and HR-MRM/PRM

Published:2016-07-08 Issue:15-16 Volume:16 Page:2106-2117
ISSN:1615-9853
Container-title:PROTEOMICS
language:en
Short-container-title:Proteomics

Author:

Nakamura Kenji¹,Hirayama-Kurogi Mio¹²³,Ito Shingo¹²³,Kuno Takuya¹⁴,Yoneyama Toshihiro⁵,Obuchi Wataru⁵,Terasaki Tetsuya⁵,Ohtsuki Sumio¹²³

Affiliation:

1. Department of Pharmaceutical Microbiology; Graduate School of Pharmaceutical Sciences; Kumamoto University; Kumamoto Japan

2. Faculty of Life Sciences; Kumamoto University; Kumamoto Japan

3. AMED-CREST; Japan Agency for Medical Research and Development; Tokyo Japan

4. Department of Drug Metabolism and Pharmacokinetics; Drug Safety Research Center, Tokushima Research Institute; Otsuka Pharmaceutical Co., Ltd; Tokushima Japan

5. Division of Membrane Transport and Drug Targeting; Graduate School of Pharmaceutical Sciences; Tohoku University; Sendai Japan

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Cabinet Office, Government of Japan

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

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5. Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT);Knights;Br. J. Clin. Pharmacol.,2013

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