Alteration of amino acid and biogenic amine metabolism in hepatobiliary cancers: Findings from a prospective cohort study

Author:

Stepien Magdalena1,Duarte-Salles Talita1,Fedirko Veronika2,Floegel Anne3,Barupal Dinesh Kumar1,Rinaldi Sabina1,Achaintre David1,Assi Nada1,Tjønneland Anne4,Overvad Kim5,Bastide Nadia678,Boutron-Ruault Marie-Christine678,Severi Gianluca9,Kühn Tilman10,Kaaks Rudolf10,Aleksandrova Krasimira3,Boeing Heiner3,Trichopoulou Antonia1112,Bamia Christina1113,Lagiou Pagona1314,Saieva Calogero15,Agnoli Claudia16,Panico Salvatore17,Tumino Rosario18,Naccarati Alessio19,Bueno-de-Mesquita H. Bas.20212223,Peeters Petra H.24,Weiderpass Elisabete25262728,Quirós J. Ramón29,Agudo Antonio30,Sánchez María-José3132,Dorronsoro Miren33,Gavrila Diana323435,Barricarte Aurelio3236,Ohlsson Bodil37,Sjöberg Klas3839,Werner Mårten40,Sund Malin41,Wareham Nick42,Khaw Kay-Tee43,Travis Ruth C.44,Schmidt Julie A.44,Gunter Marc45,Cross Amanda45,Vineis Paolo45,Romieu Isabelle1,Scalbert Augustin1,Jenab Mazda1

Affiliation:

1. Nutrition and Metabolism Section; International Agency for Research on Cancer (IARC-WHO); Lyon France

2. Department of Epidemiology, Rollins School of Public Health; Winship Cancer Institute, Emory University; Atlanta GA

3. Department of Epidemiology; German Institute of Human Nutrition, Potsdam-Rehbruecke; Nuthetal Germany

4. Diet, Genes and Enviroment Unit; Danish Cancer Society Research Center; Copenhagen Denmark

5. Department of Public Health, Section for Epidemiology; Aarhus University; Aarhus Denmark

6. Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team; Villejuif F-94805 France

7. Université Paris Sud; UMRS 1018 Villejuif F-94805 France

8. Institut Gustave Roussy; Villejuif F-94805 France

9. Human Genetics Foundation (HuGeF); Torino Italy

10. Department of Cancer Epidemiology; German Cancer Research Centre; Heidelberg Germany

11. Hellenic Health Foundation; Athens Greece

12. Bureau of Epidemiologic Research, Academy of Athens; Athens Greece

13. Department of Hygiene, Epidemiology and Medical Statistics; University of Athens Medical School; Athens Greece

14. Department of Epidemiology; Harvard School of Public Health; Boston MA

15. Molecular and Nutritional Epidemiology Unit; Cancer Research and Prevention Institute-ISPO; Florence Italy

16. Epidemiology and Prevention Unit; Fondazione IRCCS Istituto Nazionale Dei Tumori; Milan Italy

17. Dipartamento Di Medicina Clinicae Chirurgias; Federico II University; Naples Italy

18. Cancer Registry and Histopathology Unit; “Civic-M.P. Arezzo” Hospital; ASP Ragusa Italy

19. Molecular and Genetic Epidemiology Unit; HuGeF, Human Genetics Foundation; Torino Italy

20. Department for Determinants of Chronic Diseases (DCD); National Institute for Public Health and the Environment (RIVM); Bilthoven The Netherlands

21. Department of Gastroenterology and Hepatology; University Medical Centre; Utrecht The Netherlands

22. Department of Epidemiology and Biostatistics; the School of Public Health, Imperial College London; London United Kingdom

23. Department of Social and Preventive Medicine, Faculty of Medicine; University of Malaya; Kuala Lumpur Malaysia

24. Department of Epidemiology; Julius Center for Health Sciences and Primary Care, University Medical Center; Utrecht The Netherlands

25. Department of Community Medicine, Faculty of Health Sciences; University of Tromsø, the Arctic University of Norway; Tromsø Norway

26. Department of Research; Cancer Registry of Norway; Oslo Norway

27. Department of Medical Epidemiology and Biostatistics; Karolinska Institutet; Stockholm Sweden

28. Samfundet Folkhälsan; Helsinki Finland

29. Public Health Directorate; Asturias Spain

30. Unit of Nutrition, Environment and Cancer; IDIBELL, Catalan Institute of Oncology; Barcelona Spain

31. Escuela Andaluza De Salud Pública, Instituto De Investigación Biosanitaria Ibs, GRANADA, Hospitales Universitarios De Granada/Universidad De Granada; Granada Spain

32. Consortium for Biomedical Research in Epidemiology and Public Health (CIBER- CIBERESP); Spain

33. Public Health Direction and Biodonostia-Ciberesp, Basque Regional Health Department; San Sebastian Spain

34. Department of Epidemiology; Regional Health Council; Murcia Spain

35. IMIB-Arrixaca; Murcia Spain

36. Navarre Public Health Institute; Pamplona Spain

37. Department of Clinical Sciences, Division of Internal Medicine; Skåne University Hospital Malmö; Sweden

38. Department of Clinical Sciences; Lund University; Malmö Sweden

39. Department of Gastroenterology and Nutrition; Skåne University Hospital; Malmö Sweden

40. Department of Public Health and Clinical Medicine; Umeå University; Umea Sweden

41. Department of Surgical and Perioperative Sciences; Umeå University; Umea Sweden

42. MRC Epidemiology Unit; University of Cambridge; Cambridge United Kingdom

43. Clinical Gerontology, School of Clinical Medicine; University of Cambridge; Cambridge United Kingdom

44. Cancer Epidemiology Unit, Nuffield Department of Population Health; University of Oxford; Oxford United Kingdom

45. Department of Epidemiology and Biostatistics; School of Public Health, Faculty of Medicine, Imperial College; London United Kingdom

Funder

Institut National Du Cancer

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference49 articles.

1. IARC 2012 www.globocan.iarc.fr/Pages/fact_sheets_cancer.aspx

2. Hepatocellular carcinoma: epidemiology, risk factors and pathogenesis;Gomaa;World J Gastroenterol,2008

3. Epidemiology and risk factors of biliary tract and primary liver tumors;Augustine;Surg Oncol Clin N Am,2014

4. NAFLD, NASH and liver cancer;Michelotti;Nat Rev Gastroenterol Hepatol,2013

5. The metabolomic window into hepatobiliary disease;Beyoglu;J Hepatol,2013

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